Surface Chemistry in SPR Technology
نویسنده
چکیده
Whereas the previous chapters focused mainly on the physical basics of surface plasmon resonance, instrumentation and assay design, we will now turn to the heart of SPR and related biosensors: the sensor chip and its surface chemistry. It is here where the biomolecular interaction takes place and although dimensionally extremely small (the coating thickness is measured in nanometers), the sensor chip surface has a tremendous influence on the performance of a biosensor and on the quality of the data retrieved. The nanocomposite coating on a biosensor chip usually consists of the following elements, as depicted schematically in Figure 6.1:
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تاریخ انتشار 2008